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DTSTART;TZID=America/New_York:20210203T150000
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SUMMARY:Leonid Mirny\, Ph.D. - The Penn Bioinformatics Forum & The Epigenetics Institute Seminar
DESCRIPTION:IBI Flyer_3Feb2021
URL:https://epigenetics.upenndev.pendari.com/calendar/leonid-mirny-ph-d-the-penn-bioinformatics-forum-the-epigenetics-institute-seminar/
CATEGORIES:Epigenetics Special Seminars
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DTSTART;TZID=America/New_York:20210203T153000
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UID:15786-1612366200-1612368000@epigenetics.upenndev.pendari.com
SUMMARY:Leonid Mirny\, Ph.D. - Penn Bioinformatics Forum & Epigenetics Institute Seminar
DESCRIPTION:Penn Bioinformatics Forum \n \nLeonid Mirny\, PhD \nProfessor of Medical Engineering and Science\, and Physics\, Massachusetts Institute of Technology  \n“Loop extrusion with barriers as a genomic communication system” \n  \n  \nWednesday\, February 3\, 2021 \n3-4 pm\nTalk to be held online \n  \nZoom link:  \nhttps://pennmedicine.zoom.us/j/98182903599?pwd=VHRLSEwrc2pzek5FY1pycHJxTExYUT09 \nMeeting ID: 981 8290 3599 \nPasscode: 620312 \n  \nAbstract: \nThere is now strong support for the process of cohesion-mediated loop extrusion delimited by CTCF barriers as a major mechanism of interphase chromosome organization in vertebrates. However\, the role of loop extrusion in mediating functional interactions is still controversial.  Here we explore how loop extrusion with barriers may influence regulatory communication. Our models and analysis of Hi-C and Micro-C data expands the current paradigm by demonstrating that CTCF plays a dual role as both insulators and facilitators of contacts.  We propose that the system of extrusion with barriers enables a “dock-and-scan” strategy to mediate targeted functional interactions between specific elements. Taken together\, our results replace the picture of TADs as isolated regulatory neighborhoods\, with a landscape of oriented genomic communication lines established by extrusion barriers of varying strength. \n\n\n\nSponsored by the Penn Institute for Biomedical Informatics | http://upibi.org \n& the Penn Epigenetics Institute | epigenetics.upenndev.pendari.com \nTo be removed from this email list\, contact Carlos Aquino (ceduardo@upenn.edu).
URL:https://epigenetics.upenndev.pendari.com/calendar/leonid-mirny-ph-d-penn-bioinformatics-forum-epigenetics-institute-seminar/
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DTSTART;TZID=America/New_York:20210211T160000
DTEND;TZID=America/New_York:20210211T170000
DTSTAMP:20201026T112636Z
CREATED:20201026T112636Z
LAST-MODIFIED:20201026T112636Z
UID:15774-1613059200-1613062800@epigenetics.upenndev.pendari.com
SUMMARY:Bassem Al-Sady\, Ph.D. & Tong Wang (Kohli Lab) - Virtual Epigenetics Monthly Seminar Series
DESCRIPTION:Bassem Al-Sady\, Ph.D.\nAssistant Professor in Residence\nDepartment of Microbiology and Immunology\nThe G.W. Hooper Research Foundation\nThe University of California\, at San Francisco\nhttp://al-sadylab.ucsf.edu\nTwitter: @Bazzoid \n\nTrainee Talk:\nTong Wang\nMD/PhD graduate student (BMB)\, Kohli Lab\nTwitter: @tang0518 \n11Feb2021_flyer
URL:https://epigenetics.upenndev.pendari.com/calendar/bassem-al-sady-ph-d-virtual-epigenetics-monthly-seminar-series/
CATEGORIES:Epigenetics Monthly Seminar Series
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DTSTART;TZID=America/New_York:20210225T160000
DTEND;TZID=America/New_York:20210225T173000
DTSTAMP:20210405T112525Z
CREATED:20210405T112525Z
LAST-MODIFIED:20210405T112525Z
UID:15789-1614268800-1614274200@epigenetics.upenndev.pendari.com
SUMMARY:Spatial & Architectural Epigenetics Interest Group Meeting
DESCRIPTION:02.25.21 EpigeneticsSeminar_SpatialArch
URL:https://epigenetics.upenndev.pendari.com/calendar/spatial-architectural-epigenetics-interest-group-meeting-2/
CATEGORIES:Epigenetics Interest Group Meetings
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