Meta-analysis of activated neurons reveals dynamic regulation of diverse classes of alternative splicing
Keegan S Krick, Marissa Maroni, Erica Korb, Kristen Lynch, and Elizabeth Heller. Meta-analysis of activated neurons reveals dynamic regulation of diverse classes of alternative splicing. Genome Res, 2025. DOI: 10.1101/gr.280082.124 […]
MousiPLIER: A Mouse Pathway-Level Information Extractor Model
Shuo Zhang, Benjamin J Heil, Weiguang Mao, Maria Chikina, Casey S Greene, Elizabeth A Heller. MousiPLIER: A Mouse Pathway-Level Information Extractor Model. eNeuro. 2024 Jun 5;11(6):ENEURO.0313-23.2024. doi: 10.1523/ENEURO.0313-23.2024. PMID: 38789274; […]
Cell-type specific profiling of histone post-translational modifications in the adult mouse striatum
Marco D Carpenter, Delaney K Fischer, Shuo Zhang, Allison M Bond, Kyle S Czarnecki, Morgan T Woolf, Hongjun Song, Elizabeth A Heller. Cell-type specific profiling of histone post-translational modifications in […]
Cocaine regulation of Nr4a1 chromatin bivalency and mRNA in male and female mice
Delaney K Fischer, Keegan S Krick, Chloe Han, Morgan T Woolf, Elizabeth A Heller. Cocaine regulation of Nr4a1 chromatin bivalency and mRNA in male and female mice. Sci Rep. 2022 […]
Chromatin-mediated alternative splicing regulates cocaine-reward behavior
Song-Jun Xu, Sonia I Lombroso, Delaney K Fischer, Marco D Carpenter, Dylan M Marchione, Peter J Hamilton, Carissa J Lim, Rachel L Neve, Benjamin A Garcia, Mathieu E Wimmer, R […]
Specific histone modifications associate with alternative exon selection during mammalian development
Qiwen Hu, Casey S Greene, Elizabeth A Heller. Specific histone modifications associate with alternative exon selection during mammalian development. Nucleic Acids Res. 2020 May 21;48(9):4709-4724. doi: 10.1093/nar/gkaa248. PMID: 32319526; PMCID: […]
Nr4a1 suppresses cocaine-induced behavior via epigenetic regulation of homeostatic target genes.
Carpenter MD, Hu Q, Bond AM, Lombroso SI, Czarnecki KS, Lim CJ, Song H, Wimmer ME, Pierce RC, Heller EA. Nat Commun. 2020;11(504). doi: 110.1038/s41467-020-14331-y.
Sex-Specific Regulation of Fear Memory by Targeted Epigenetic Editing of Cdk5.
Sase AS, Lombroso SI, Santhumayor BA, Wood RR, Lim CJ, Neve RL, Heller EA. Biol Psychiatry. 2019 Apr 15;85(8):623-634. doi: 10.1016/j.biopsych.2018.11.022. Epub 2018 Dec 5. PMID:30661667
Histone posttranslational modifications predict specific alternative exon subtypes in mammalian brain
Histone posttranslational modifications predict specific alternative exon subtypes in mammalian brain Hu Q, Kim EJ, Feng J, Grant GR, Heller EA. PLoS Comput Biol. 2017 Jun 13;13(6):e1005602.